pentobarbital will lessen the extent or result of etravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.Watch Intently (one)pentobarbital will lower the level or influence of tofacitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. Lack of, or reduced response to tofacitin